摘 要目的 探讨高血压( Hypertension)与尿酸、血脂和肌酐的相关性,为高血压的干预和 并发症的预防提供科学依据,为疗养院及临床的高血压管理提出建议。方法 本研究以 2016
年在杭州某养老院体检的 3256 名体检人群为研究对象,通过该人群的体检数据进行基础统 计学描述、卡方检验、Pearson 相关性分析及 Logistic 回归分析等方法,对高血压与尿酸、血 脂和肌酐的关系进行研究。结果 不同性别和年龄在高血压患病情况上有显著差异(P<0。00 1);总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固 醇(LDL-C)、肌酐(Cr)水平高血压组显著高于非高血压组(P<0。001);高血压组中男性的 TC、TG、HDL-C、LDL-C、Cr 水平显著高于非高血压组中男性(P<0。05);高血压组中女性的 TC、TG、LDL-C、血尿酸(UA)水平显著高于非高血压组中女性(P<0。05);高血压组内女 性的 TC、HDL-C 水平显著高于男性(P<0。05);高血压组内青年、中年和老年组的 TC、TG、 HDL-C 和 Cr 的指标均数间有差异(P<0。05);Pearson 相关分析:血压值与年龄(Age)、TC、 TG、HDL-C、LDL-C 呈正相关(P<0。001);Logistic 回归分析:年龄、性别、TC、TG、LDL-C、 HDL-C 是高血压的危险因素(P<0。05),其中高密度脂蛋白胆固醇的危险度最高(OR 值为 1。 794,95%CI:1。160-2。774)。结论 高血压与血脂、尿酸、肌酐有着密切关系;性别、年龄、 总胆固醇、甘油三酯、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇是高血压的危险因素。88978
毕业论文关键词:高血压; 肌酐; 血脂;尿酸;相关性
Abstract Objective To investigate the correlation between hypertension (Hypertension) an d blood lipid, uric acid and creatinine, and provide scientific basis for preventi on and intervention of hypertension and complication, recommendations for hyp ertension and clinical management of sanatorium。 Methods in this study, in 20 12, 3256 adults in Hangzhou a nursing hospital as the research object, basic st atistical description, chi square test, Pearson correlation analysis and Logistic re gression analysis were used by physical examination data of the population, the study on the relationship between hypertension and serum lipids, urine acid a nd creatinine。 Results Different gender and age in the prevalence of hypertensi on has significant difference (P < 0。001); total cholesterol in hypertension grou p (TC), triglyceride (TG), high density lipoprotein cholesterol (HDL-C), low de nsity lipoprotein cholesterol (LDL-C), creatinine (Cr) levels were significantly h igher in non hypertension group (P < 0。001); in the hypertension group TC, T G, male HDL-C, LDL-C and Cr were significantly higher than that of male no n hypertension group (P < 0。05); in the female group, TC, TG, LDL-C, hypert ension, blood uric acid (UA) levels were significantly higher than that of fema le group in non hypertension group (P < 0。05); In the female group, TC, TG, LDL-C, hypertension, blood uric acid (UA) levels were significantly higher in female non hypertension group (P < 0。05);