摘要：卟啉是一类重要的有机大环配体，具有高度共轭的平面结构和生色基团，是性能优异的光敏材料，在光电器件、催化、分子识别等不同领域都有广泛应用。许多天然卟啉以及它的金属化合物都在生命活动中起着关键作用。卟啉在我们的生活中也有着重要的应用，比如作为半导体材料用于材料化学，作为癌症的诊断工具用于医学，或者是用于能源化学方面等。本文以对羟基苯甲醛、吡咯和醋酸钴为主要原料，丙酸为溶剂，利用普通的回流法对四羟基苯基卟啉钴的合成进行了初步探索，并且探索了温度和反应时间对合成的影响。在实验过程中，通过测试反应液的紫外可见吸收光谱监测反应进程。利用紫外可见光谱、红外光谱、质谱和核磁共振光谱对产物进行了表征，结果表明我们已经制备得到了目标产物，四羟基苯基卟啉钴。36885
毕业论文关键字：金属卟啉钴；合成；提纯；表征。
Synthesis and characterization of tetrahydroxyphenyl porphyrin cobalt
Abstract: Porphyrin is a kind of important organic macrocyclic ligands, with highly conjugated planar structures and chromophore, photosensitive materials with excellent properties, and are widely used in different areas of the optoelectronic devices, catalysis, molecular recognition. Many natural porphyrin and its metal compounds play a key role in life activities.. Porphyrin in our life also has important applications, such as as a semiconductor material for chemical materials, cancer as a diagnostic tool for medical, or is used to chemical energy. The to the hydroxy benzaldehyde and pyrrole and cobalt acetate as main raw material and propionic acid as solvent, using ordinary refluxing for 4 hydroxyphenyl porphyrin cobalt synthesis were preliminary exploration, and explore the temperature and reaction time on synthesis was studied. During the experiment, the reaction process was monitored by UV visible absorption spectrum of the reaction liquid.. The products were characterized by UV Vis, IR, MS and NMR, and the results showed that the products were prepared and four hydroxy phenyl porphyrin was prepared.
Keyword: cobalt porphyrin; synthesis; purification; characterization.
目录
1 前言 1
1.1 卟啉及卟啉化合物概述 1
1.2 卟啉的合成方法 2
1.2.1 Rothmund法 2
1.2.2 Adler-Longo法 3
1.2.3 Lindsey 法 4
1.2.4 Macdonald 法 4
1.2.5 微波诱导法 5
1.2.6 2-取代基吡咯法合成卟啉 5
1.2.7 3+1法 6
1.2.8 线性四吡咯法 6
1.2.9 其它方法 7
1.3 金属卟啉的合成 7
1.3.1 在中性溶液中反应 7
1.3.2 在酸性溶液中反应 7
1.3.3 在弱碱性溶液中反应 7
1.3.4 在强碱性溶液中反应 8
1.3.5 固相法 8
1.4 卟啉和金属卟啉的应用 8
1.4.1 卟啉在材料化学上的应用 8
1.4.2 卟啉在医学上的应用 8
1.4.3 卟啉在生物化学方面的应用 9
1.4.4 卟啉在分析化学方面的应用 9
1.4.5 卟啉在能源化学方面的应用 10
1.4.6 卟啉在地球化学方面的应用 10
1.4.7 在催化化学的应用 10
2 卟啉及其化合物的分析方法 11
2.1 紫外光谱分析[21] 11
2.2 红外光谱分析[23,24] 11
2.3 核磁共振谱图 11
2.4 质谱分析图 12
3 立题依据 13 四羟基苯基卟啉钴的合成与表征:http://www.youerw.com/yixue/lunwen_35540.html