摘要：
现在市场上所存在的植入式神经刺激器都存在这样或那样的缺点。例如：刺激脉冲比较单一，设备供电寿命短的缺点。基于这些问题，我们提出了一种新型的双极性神经刺激脉冲发生器。主要的内容有以下几个方面：提出了双极性神经刺激脉冲发生器以及无线通信两个模块的总的设计方案。方案给出了各个模块的硬件与软件的详细设计思想与实现方法。
首先完成了双极性神经刺激器系统样机的研制、各个模块的功能测试以及整个系统的联合调试。实现了：1）用单片机产生两路PWM波，经过升压电路提升电压，再经过H桥电路输出所需要的刺激脉冲；2）完成了双极性神经刺激器系统的软硬件调试，脉冲的频率、占空比以及幅度都可以通过无线通信装置来调控（频率在1-1200Hz可调，脉冲占空比在1%-49%可调，脉冲幅度在0-10mA可调）。
然后在设计的制作过程中我们首先需要通过仿真完成对各个模块的功能进行模拟，然后再通过面包版进行测试，最后在PCB板上进行实物验证。最终我们克服种种困难完成了脉冲发生电路、脉冲调幅电路、数据采集电路、频率和占空比调节电路的设计。并最终通过了测试和完成了动物实验。
本设计实现了双极性神经刺激器的初步要求，如准备将该系统用于临床使用，该系统还存在着体积过大、系统可靠性等问题。所以在本文最后还将针对设计中所发现的不足之处为以后的工作指出一个方向。
关键词：双极性；刺激器脉冲；无线通信；调控；PWM波；治疗
Abstract：Implantable neuro stimulator exists on the market today there are so many disadvantages. For example: single pulse stimulation, power supply equipment short life shortcomings. Based on these problems, we propose a new type of bipolar nerve stimulation pulse generator. The main contents are as follows：Firstly the general
design scheme of two modules of bipolar nerve stimulator and wireless communication is put forward. The detailed design idea and implementation method of each module's hardware and software are given ； Secondly completed the development of bipolar nerve stimulator system prototype, debugging function testing of each module and the whole system. To achieve this goal we have two points to do:
1) using single-chip microcomputer to produce two PWM wave, after the boosting circuit boosts a voltage, then output through H bridge circuit to stimulate pulse; 2) completed the hardware and software of bipolar nerve stimulator the debugging of the system, pulse frequency, duty cycle and amplitude can be controlled by the wireless communication device (1-1200hz in frequency adjustable pulse duty ratio adjustable, 1%-49% pulse amplitude adjustable at 0-10mA).
In the design process we need to complete the simulation of the function of each module is simulated, and then through the bread version for testing, final physical verification in the PCB board. Finally, we overcome the difficulties to complete the pulse generating circuit, pulse modulation circuit, data acquisition circuit, frequency and duty ratio control design circuit. And finally passed the test and the animal experiments.
The design and implementation of the preliminary requirements of bipolar nerve stimulator, such as preparing the system for clinical use, the system also has the volume is too large, the reliability of the system. So in the end of this paper will also put forward the improvement plan of the next step.
Keywords: bipolar; nerve stimulator; wireless communication; regulation
目录
第一章绪论 1
1.1课题研究背景及意义 1
1.2神经刺激器的国内外研究现状 单片机双极性神经刺激脉冲发生器的设计:http://www.youerw.com/tongxin/lunwen_203589.html