摘 要超分子水凝胶一般由分子量较低的化合物通过非共价键作用形成的空间网络结构。由于 这种结构间隙中含有大量的水而成为一种软物质。超分子水凝胶由于无毒，生物相容性好- 与人类的组织细胞相似的特点，广泛地受到外界的关注。基于非共价键的可逆作用，超分子 水凝胶往往具有多重刺激响应性（如热、pH、光和电等）、自修复性能等。到目前为止，对 于荧光超分子水凝胶的研究较少。88514

为此，本文将具有聚集诱导效应（AIE）的四苯基乙烯基团（TPE）引入到超分子水凝 胶的构建中，期望得到一种荧光超分子水凝胶。本文设计合成了一头带有金刚烷的三联吡啶 衍生物的水溶性盐 D1 和以 TPE 为核，两端分别为水溶性的 β-CD 的分子 D2。D1 分子水溶 液能与 Zn2+进行金属配位形成二聚体，进一步加入分子 D2，便可以与二聚体自组装形成线 型超分子聚合物。最后，通过提高线型超分子聚合物的浓度，便能得到一种荧光超分子水凝 胶。我们通过紫外滴定来表征二聚体的合成；用核磁和 2D ROESY 来表征主客体相互作用； 用荧光和流变来表征线型聚合物的生成。

毕业论文关键词：二聚体；超分子水凝胶；荧光。

Abstract Supramolecular hydrogels are generally composed of low molecular weight compounds through the non-covalent bond and form the space network structure。 Because the gap of the structure contains a lot of water and becomes a soft substance。 Supramolecular hydrogels are widely  non-toxic,  biocompatible–similar  to  the human tissue cells and is paid wide range of attention by the outside world。 Based on the reversible effect of noncovalent bonds, supramolecular hydrogels tend to have multiple stimulus responsiveness (eg, heat, pH, light and electricity), self-repairing properties and so on。 So far, less research has been done on fluorescent supramolecular hydrogels。

In this paper, tetraphenylvinyl group (TPE) with aggregation induction effect (AIE) was introduced into the construction of supramolecular hydrogels, and hope to obtain a fluorescent supramolecular hydrogel。 So we designed and synthesized a water-soluble salt D1 with a diphenylpyridine derivative with adamantane and a molecule D2 with TPE as the core and both ends of the water-soluble β-CD。 D1

molecular aqueous solution can form a dimer with Zn2+, and by adding molecular D2,

the dimer can form a linear supramolecular polymer by self-assemble。  We characterize the synthesis of dimer by UV titration; The interaction between host and guest was characterized by 1H NMR and 2D ROESY; Iinear polymers were characterized by fluorescence and rheology。

Key words: Dimer; Supramolecular hydrogel; Fluorescent

目 录 

摘 要 I

Abstract II

1．前言 1

1。1 基于环糊精的超分子源Y于Y优E尔Y论L文W网wwW.yOueRw.com 原文+QQ752018.766 水凝胶的介绍 1

1。2 基于环糊精的超分子水凝胶的优点 2

1。3 基于环糊精的超分子水凝胶的应用 3

1。 4 研究目的 5

2。实验部分 6

2。1 实验仪器 6

2。2 实验步骤 7

2。3 表征结果 7

2。3。1 基于分子 D1 与金属锌离子形成二聚体 M1 的表征