摘要：论文的主要目标是研究氧化芳樟醇在间氯苯过甲酸做氧化剂的情况下所进行的化学反应过程，该过程主要是氧化芳樟醇通过与氧化剂间氯苯过甲酸所进行的环氧化反应，从而得到产物2-[5-甲基-5-(环氧-2-基)四氢呋喃]丙醇-3，接着对产物进行提纯及波谱分析。实验过程中在氧化芳樟醇中加入一定量的二氯甲烷与饱和碳酸钠，冰水浴0-5℃，磁力搅拌均匀。在回流、磁力搅拌的条件下，加入纯度为85%的间氯苯过甲酸溶液，控制反应温度为0-10℃，反应4小时，得到2-[5-甲基-5-(环氧-2-基)四氢呋喃]丙醇-3及可能的其他副产物。并对其进行抽滤、洗涤、干燥等一系列后处理步骤后，得到较纯的最终的目标产物，即2-[5-甲基-5-(环氧-2-基)四氢呋喃]丙醇-3。其中，利用洗涤萃取的方法对产物进行提纯，依次用一定量的饱和亚硫酸钠（2次），一定量的饱和碳酸氢钠，一定量的饱和氯化钠（2次），对抽滤过后的溶液进行洗涤，之后向所得溶液中加入无水硫酸钠进行干燥过夜。最终将实验所得产物进行GCMC波普分析，从而确定反应的产物是2-[5-甲基-5-(环氧-2-基)四氢呋喃]丙醇-3而不是其他物质。根据记录下来的相关数据计算得出实验产率达到71.99%。69485

毕业论文关键词；氧化芳樟醇；间氯苯过甲酸；环氧化反应；波普分析；2-[5-甲基-5-(环氧-2-基)四氢呋喃]丙醇-3

The Study of The Epoxy Reaction of Linalool 

Abstract: The main goal of the paper is the study of oxidation of aromatic camphors alcohol in the case of chlorobenzene performic acid do between oxidant by chemical reaction process, this process is mainly by oxidizing aromatic camphors alcohol and antioxidant effects of performic acid by epoxidation reaction, thus to the product of 2 - [5 - methyl - 5 - (epoxy - 2 -) tetrahydrofuran] propyl alcohol, then the separation, purification and structure identification of the product. Experiments on oxidation of aromatic camphors alcohol adding a certain amount of methylene chloride with saturated sodium carbonate, ice water bath 0-5 ℃, magnetic stir to mix well. Under the condition of reflux, magnetic stirring, adding the purity of 85% between chlorobenzene performic acid solution, control the temperature of 0 to 10 ℃, the reaction of 4 hours, get a 2 - [5 - methyl - 5 - (epoxy - 2 -) tetrahydrofuran] propyl alcohol - 3 and possibly other by-products. And the suction filter, washing, drying, after a series of post-processing step to get a pure product of the final goal of 2 - [5 - methyl - 5 - (epoxy - 2 -) tetrahydrofuran] propyl alcohol - 3. Among them, the washing solvent extraction method is used to analyse the product purification, in turn, with a certain amount of saturated sodium sulfite (twice), a certain amount of saturated sodium bicarbonate, a certain amount of saturated sodium chloride (twice), solution of the suction filter after washing, to join the anhydrous sodium sulfate in the solution obtained after drying for the night. The GCMC pop analysis, product will eventually experiment to determine the reaction product is 2 - [5 - methyl - 5 - (epoxy - 2 -) tetrahydrofuran] propyl alcohol - 3 rather than other substances. Based on the relevant data recorded, the yield rate reached 71.99%.

Key words; Linalool. M-chlorobenzoic acid; Epoxy reactions; Spectral analysis; 2 - [5 - methyl - 5 - (epoxy - 2 -) tetrahydrofuran] propyl alcohol - 3.

目  录

1 前言 5

1.1背景 5

1.2环氧化反应 6

1.3文献合成方法 7

1.3.1 过酸进行的环氧化反应 7

1.3.2 二氧烷（Dioxiranes）进行的环氧化反应