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摘要：光学相干层析成像是20世纪90年代逐步发展而成的一种新的三文层析成像技术。OCT基于低相干干涉原理获得深度方向的层析能力，通过扫描可以重构出生物组织或材料内部结构的二文或三文图像，其信号对比度源于生物组织或材料内部光学反射（散射）特性的空间变化。它可以获得高分辨率的组织结构图像，并且具有非接触、无伤害等优点。OCT技术因其显著优点，在生物医学中具有其他检测方式无可比拟的优势，在眼科、心血管等医学领域得到广泛的应用。本文首先对OCT的定义、分类、特性与发展进行分析；然后在此基础上对OCT技术中光在生物组织中传播模型与特性以及OCT系统的理论原理进行研究；最后，分析OCT技术在医学各领域的应用情况。37774
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毕业论文关键词：光学相干层析技术；生物组织；生物医学应用
Application of optical coherence tomography in biomedicine
Abstract: Optical coherence tomography is a new 3D tomography technology developed in the 90 time in twentieth century. OCT is based on the principle of low coherence interferometry, and can reconstruct 2D or 3D images of the structure of biological tissues or materials by scanning.The signal contrast is derived from the spatial variation of optical reflectance (scatter) in biological tissues or materials. which can get high-resolution images of tissue structure, and has prominent advantages such as non-contact, no harm, biopsies.Contrast to other detection methods, because of the significant advantages of OCT ,it has unparalleled advantage in biomedicine, so that OCT has been widely used in the field of ophthalmology, cardiovascular medicine. Firstly, definition, classification, characteristics and development of OCT are analyzed. Secondly, on the basis of the previous study, theoretical principles of light propagation model characteristics and OCT systems in biological tissue are analyaed. Finally, the application of OCT technology in all areas of medical are researched.
Keywords: Optical coherence tomography; Biological tissue; Biomedical Application
目录
1 绪论 2
1.1 研究背景与意义 2
1.1.1 研究背景 2
1.1.2 研究意义 2
1.2 文献综述 2
2 OCT基本介绍 4
2.1 OCT的定义与分类 4
2.1.1 偏振OCT 5
2.1.2 多普勒OCT 6
2.1.3 光谱OCT 6
2.2 OCT的特点 6
2.2.1 优点 6
2.2.2 局限性 7
2.3 OCT的历史发展 7
3 OCT的理论分析 7
3.1 OCT的理论基础 7
3.1.1 光在生物组织内部的传播模型 7
3.1.2 光在生物组织内部的传播特性 8
3.2 OCT系统的工作原理 10
4 OCT在生物医学中的应用 10
4.1 OCT现阶段的应用 11
4.1.1 眼科 11
4.1.2 心血管 13