全场光学相干层析术的信号探测技术研究
毕业论文关键词：全场光学相干层析成像 分辨率 成像深度 散射补偿 像差
毕业设计说明书外文摘要
Title Study of Signal Detection Techniques in Full optical coherence tomography
Abstract
Full optical coherence tomography can generate high resolution optical sectioning images and has great application potential in the field of the biomedical medicine. It is mainly based on the detection of the light backward scattered from biological tissue, and the light from the sample is superposed with the light reflected from the reference arm of the interferometer and generate interference fringes. The information about the object can be obtained by measuring the envelope of the interference envelope. In this device a light source with broad bandwidth and the microscopic objective lenses with high numerical apertures are used to obtain high depth and the transverse resolution.The CCD is employed to detect the imaging signal and a high imaging speed can be achieved.In this work, the signal measured by a FFOCT system based on the combination of the Linnik interference microscope and the Koller illumination were processed and optimiaed to improve the imaging speed. First of all, the imaging principles were considered and a FFOCT system was established. The genaration of the imaging signal, detection and processing were discussed. The imaging performance were then analyzed with theamphasis on the imaging depth and the resolution. The light sacttering model of tissue was discussed and the signal attenuation induced by the scattering wrere compensated to increase the image contrast, which is helpful for imaproving the imaging depth in the future.
Keywords Optical coherence tomography resolution Imaging depth Scattering compensation aberration
目 次
1 引言 1
1.1 生物组织成像的现状与发展趋势 1
1.2 光学相干层析成像研究的发展历程 3
1.3 本课题研究的内容与改进 4
2 全场光学相干层析成像的理论基础 5
2.1 OCT的原理与FFOCT的原理 5
2.2光源 7
2.3 照明系统 7
2.4 干涉仪 9
2.5信号采集 9
3 系统成像性能分析 12
3.1 纵向分辨率 12
3.2 横向分辨率 13
3.3 成像中的噪声 14
3.4 生物组织中散射模型 15
3.5 成像深度的分析及优化 17
4 全场光学相干层析成像的实验与结果 18
4.1 实验系统成像与图片采集 18
4.2 生物组织引起的像差的影响及其补偿 19
4.3 实验结果 20
结论 22
致谢 23
参考文献24
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