基于扫频光源的人体血流成像研究
关键词 扫频光学相干层析术；手持式；信噪比；灵敏度；血流速度
毕业论文设计说明书外文摘要
Title The Study of Human Body Blood Flow Imaging Based on The Swept Source
Abstract
In this paper, a handheld swept source optical coherence tomography (SSOCT) system is described for imaging human blood flow. First of all, the performance of the system is analyzed in detail, and compared with ones of the spectral domain optical coherence tomography (SDOCT) system in our Lab. Then, a phantom experiment and several in vivo experiments on different areas of human skin were implemented to demonstrate the performance of the handheld SSOCT in terms of the signal to noise (SNR) and the maximum imaging depth, showing that the handheld SSOCT can image any part of human skin. Finally, a phantom experiment with glass capillary filled with milk simulating the blood flow was implemented .All the results indicate that the handheld SSOCT setup developed in this work cannot only image any part of the skin conveniently, but also generate the images of both the structure and the blood flow with high quality.
Keywords swept source optical coherence tomography；handheld；the maximum imaging depth；SNR；sensitivity
目 次
1. 绪论 1
1.1 OCT技术概述 1
1.2 OCT技术原理与分类 1
1.2.1时域OCT 1
1.2.2傅里叶域OCT 1
1.3 OCT技术发展与应用 2
1.3.1 时域OCT 2
1.3.2 谱域OCT 3
1.3.3 扫频OCT 3
1.4 多普勒OCT的发展 3
1.4.1 多普勒OCT的原理 4
1.4.2 多普勒OCT方法的实现 5
1.4.3 多普勒OCT方法的应用 6
1.5 本课题主要研究问题与创新点 7
1.6 本文内容安排 7
2. 扫频OCT基本理论 8
2.1 扫频OCT概述 8
2.2 扫频OCT性能指标 9
2.2.1 成像深度 9
2.2.2 分辨率 9
2.2.3 信噪比 10
2.2.4 灵敏度 10
3. 手持式扫频OCT系统搭建 11
3.1 系统硬件设计 11
3.2 数据采集 14
3.3 数据处理与结构图像重建 15
3.4 血流图像重建 15
4. 实验与结果分析 16
4.1 系统参数测定 16
4.2 结构模拟实验 20
4.3 人体皮肤活体实验 21
4.4 血流模拟实验 23
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