COMSOL片上实验室的多相微流操控

摘要本文首先通过国内外文献调研，了解了片上实验室系统的研究历史与现状，以及典型多物理场耦合片上系统的工作原理。然后学习使用了COMSOL软件，建立典型的围绕微流场系统（Micro Fluidic Systems）的微通道模型，用以实现目标样本输运过程中的高精度流量控制。针对微通道液滴速度的影响的问题，基于COMSOL对于不同几何结构或者尺寸大小微通道进行建模，一共建立了四种几何结构并且分别具有11中不同尺寸的为通道模型，仿真这些微通道对于两相微流体速度的影响，其中包括对于速度大小以及速度方向的影响，紧接着本文将对于仿真结果进行分析和讨论，最终得到了扩大尺寸可以降低液滴流速以及三角形是最佳降低流速的通道模型的结论，并且阐述了各个通道的优势与不足。80066

毕业论文关键词微流控液滴微通道几何结构速度

毕业设计说明书外文摘要

Title Lab-on-chip microfluidic manipulation of multiphase

Abstract Firstly,we have studied the history and status quo on research lab-on-chip system through literature researching，we have also studied the theory on the the typical multi-physics coupling system on chip。 Then we learned to use the COMSOL software to build a typical MFS micro-channel model to achieve the target sample transport process in precision flow control。For the affects on the velocity of droplets，we tried to build the microchannels modeling with different geometry or size，and we have established 4 channel models with 11 different sizes。After that we simulated the influence on the velocity of two-phase microflu by the channel，both the influence on the rate and the direction。 Then we have analyzed and discussed the result of the simulation。 Finally，we find that expanding the size of channel is a effective way to reduce the velocity of the droplets，and the channel with a geometry of the triangle is the best one。We also tried to expound the advantage and disadvantage of each channel。

Keywords microfludic droplet microchannel geometry velocity

1 引言 1

1。1 国外研究进展 1

1。2本文研究工作 5

2 研究方法 6

2。1 理论模型 6

2。2 数值仿真模型 7

3 典型数值仿真结果 9

3。1椭圆扩张/内凹结构 9

3。2矩形/内凹扩张结构 10

3。3 三角形扩张/内凹结构 11

3。4圆环形分离结构” 12

3。5 通道中的流线状态 13

4 讨论与分析 14

4。1改变微通道几何结构实现对于液滴流量的操控 14

4。2 圆环通道的作用 17

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