摘  要：本论文主要设计合成具有新颖结构和性质的多金属氧酸盐，以Anderson型杂多酸为切入点，在多酸上引入功能化的有机基团。通过Tris-NH2修饰的Fe-Anderson型杂多酸与(S)-1-(1-苯乙基)异硫氰酸酯合成(S)-1-(1-苯乙基)硫脲修饰的Fe-Anderson型杂多酸催化剂的反应。该方法将硫脲小分子单侧共价修饰到Fe-Anderson型杂多酸上，使得小分子的酸性增强，催化剂的活性提高，从而减少催化剂的用量。另外，我们还研究了Tris-NH2修饰的多酸为催化剂催化苄胺生成亚胺的反应。本研究不仅丰富了多金属氧酸盐的结构，而且扩大了多酸的应用范围。62207

毕业论文关键词：  杂多酸；单侧修饰；硫脲；催化

The design and synthesis of Fe-Anderson heteropoly acid catalyst modified by (S) -1- (2- hydroxy -1- ethyl benzene) thiourea

Abstract：A novel approach for the design and synthesis of polyoxometalates has been developed in this thesis, functional groups are introduced into the Anderson-type heteropolyacid which was as the starting point. The synthesis of (S)-1-(1-phenylethyl) thiourea modified Fe-Anderson-type heteropoly catalyst by Tris-NH2-modified Fe-Anderson-type heteropolyacid and (S) -1- (1- phenylethyl) isothiocyanate. Thiourea molecules was modified in the one side of Fe-Anderson-type heteropolyacid by the covalent modification that enhanced the acid of small molecule and improved the activity of the catalyst, thereby reducing the catalyst dosage. In addition, we also studied the reaction Tris-NH2 modified acid as Catalyst benzylamine generated imine. This study not only enriches the structure of the multi metal oxide, but also expands the application range of polyoxometalates.

Key Words: Heteropolyacids、Unilateral modification、Thiourea、catalytic

1前言 3

 1.1 研究背景……...3

 1.2 Anderson结构多酸的发展…4

 1.3 Anderson结构多酸的应用……9

   1.3.1在催化方面的应用 9

   1.3.2在药物方面的应用 9

 1.4硫脲催化剂的制备及发展 9

   1.4.1硫脲合成的发展 9

   1.4.2异硫氰酸酯合成的发展 10

 1.5小结……...12

 1.6研究意义...12

2实验部分 13

 2.1试剂与仪器 13

   2.1.1试剂 .13

   2.1.2实验仪器14

 2.2实验内容……...14

   2.2.1 Fe-Anderson型杂多酸母体Na3[Fe(OH)6Mo6O18]的制备..14

   2.2.2 Fe-Anderson型杂多酸母体(NH4)3[Fe(OH)6Mo6O18]的制备……..15

   2.2.3单侧氨基修饰的Fe-Anderson型多金属氧酸盐的制备.16

   2.2.4 (S)-1-(1-苯乙基)异硫氰酸酯的制备步骤..16

   2.2.5(S)-1-(1-苯乙基)硫脲修饰的Fe-Anderson型多金属氧酸盐的制备16

   2.2.6 Tris-NH2修饰的Fe-Anderson型杂多酸催化剂的应用...17

3结果与讨论…….. 18

 3.1结果……... 18

   3.1.1多酸母体的制备... .18

   3.1.2 Tris-NH2修饰的Fe-Anderson型杂多酸的制备..18

   3.1.3 (S)-1-(1-苯乙基)异硫氰酸酯的制备 18

   3.1.4(S)-1-(1-苯乙基)硫脲修饰的Fe-Anderson型多金属氧酸盐的制备...18

   3.1.5 Tris-NH2修饰的Fe-Anderson型杂多酸催化剂的应用...18