摘要：OCT技术是近年来较为广用的与光有关的检测方法，其中具有不伤害细胞表层、非侵入等特点。该技术包含了光电科学信息技术、计算机技术等学科。OCT技术根据迈克尔逊干涉仪与显微共焦技术，主要测量生物组织细胞的背向散射光的延迟信息从而得到二维或者三维的结构成像，对活体细胞进行无损检测，简称“光学活检”。OCT技术可以准确实时的进行检测，分辨程度大致在1-14。5μm，成像的深度达到2-3。1mm。其中OCT中的光在组织细胞中不断进行发散，会造成散射、被细胞表层接收和发射。所以光学成像技术一般发生在光可以直接达到或者利用光学工具到达的细胞组织中。又因为光最容易到达的是分布于眼部范围的组织表面，所以OCT在眼科领域应用十分理想。又因为光学成像技术的深度限制，OCT技术能和导管、内窥镜等设备相连接，对肿瘤的探测和临床试验也有很大的帮助，扩大了OCT技术的实用范围。87941

本课题通过已有OCT系统对部分细胞实现亚微米级分辨率并对细胞作出分析。

毕业论文关键词：光学相干技术、微米级程度、细胞

Design of OCT Micrometer system

Abstract：Optical coherence tomography (optical coherence tomography) is a widely used optical detection technology in recent years。 It has no harm to tissue cell and non invasion。 The technology includes Optoelectronic Science and information technology, computer technology and other disciplines。 OCT technology is based on Michelson interferometer and confocal microscopy。 It is mainly used to measure the delayed information of backscattered light of biological tissue cells to get two-dimensional or three-dimensional structure imaging, and non-destructive detection of living cells, referred to as optical biopsy。 OCT technology can be detected accurately in real time, the resolution is approximately 1-14。5 m, and the depth of imaging reaches 2-3。1mm。 Light can be propagated in a biological tissue to cause scattering, absorption and emission。 So the optical imaging technology usually occurs in the cell tissue that can be reached directly or by the use of optical tools。 And because light is the most easy to reach the eye area of the tissue surface, so the application of OCT in the field of ophthalmology is very ideal。 Because of the limitation of optical imaging technology, OCT technology can connect with catheters, endoscopy and other devices。 It also helps greatly in tumor detection and clinical trials, and expands the practical range of OCT technology。源-于,优Y尔O论U文.网wwW.youeRw.com 原文+QQ75201,8766

Through the existing OCT system, the submicron resolution of some cells is realized and the cells are analyzed。

Key words: optical coherence tomography, micron resolution, cell

第一章 绪论 2

1。1课题的目的和意义 2

1。2国内外研究现状和发展趋势 2

1。3文献综述 2

第二章 OCT技术的简明概述 3

1。1 光学相干层析技术的产生背景 3

1。1。1 X射线 3

1。1。2 放射性核素成像 3

1。1。3 超声波 3

1。1。4 核磁共振 3

1。2光学相干层析技术的定义 4

第三章 OCT技术对细胞实现分辨率为亚微米级的过程 4

2。1实验器材及分析