摘要目的 探讨血脂组成成分与动脉硬化关键指标之间的相关性，为明确心脑血管疾病的发病原 因提供参考。方法 通过对温州某三甲医院 1905 例体检人群进行人口学资料、血脂、脉搏波 传导速度、踝臂指数等指标进行测量，利用独立样本 t 检验、单因素方差分析、Pearson 相 关、logistic 回归、多远线性回归分析等方法，对血脂与动脉硬化的相关性进行研究 结果 独立样本 t 检验显示：不同血脂、血压、尿酸、性别组别的 ABI、baPWV 值的差异有统计学 意义。单因素方差分析显示：不同年龄、BMI 组别的 ABI、baPWV 值的差异有统计学意义。 Pearson 相关分析显示：在置信度为 0。01 时，性别只与 baPWV 有相关，且为负相关。年龄、 BMI、收缩压、舒张压、尿酸、TC、TG、LDL-C 与 ABI、baPWV 有显著正相关性（p <0。05）， 其中年龄（r =0。655，p <0。001）、收缩压（r =0。618，p <0。001）与 baPWV 的相关性较强， 而 LDL-C 与 ABI、baPWV 呈负相关。Logistic 回归分析表明：所有自变量都不是 ABI 值的影 响因素，血脂对 ABI 值没有影响。多元线性回归分析表明：年龄、收缩压、舒张压、尿酸、 BMI、TG、TC 是影响 baPWV 的重要因素，即年龄越大，血压越高，尿酸越高，TG 值越高，baPWV 值越高。结论 血脂与 ABI 无相关性，年龄、收缩压、舒张压、尿酸、BMI、TG、TC 与 baPWV 相关，血脂与动脉硬化无明显相关。88147

Abstract Objective to investigate the serum lipids and atherosclerosis and the relationship between components, to provide a scientific basis for the pathogenesis of clear cardiovascular and cerebrovascular disease and its prevention and health intervention。 Methods The demographic data of a hospital in Wenzhou 1905 cases of health examination, investigation of risk factors for cardiovascular disease, and blood pressure, blood lipid, pulse wave velocity index the application of Pearson, correlation, logistic regression, far linear methods such as regression  analysis,  correlation on blood lipids and atherosclerosis were studied。 Result Independent samples t test showed that: different blood lipids, blood pressure, uric acid, sex group ABI, the difference was statistically significant baPWV value。 Single factor variance analysis showed that different age groups BMI, ABI, baPWV difference was statistically significant。Pearson correlation analysis showed that: under 0。01 confidence, the sex only with baPWV related, and is negative correlation。 The age, BMI, systolic blood pressure, diastolic blood pressure, uric acid, TC, TG, LDL-C and ABI, has  a significant positive correlation between baPWV (P <0。05), age (R =0。655, P <0。001), systolic blood pressure (R =0。618, P <0。001) and the strong correlation between baPWV and LDL-C。 With ABI, baPWV was negatively related to the。Logistic regression analysis showed that factors affecting all variables are not ABI value, ABI value has no effect on serum lipid。 Multivariate linear regression analysis showed that age, systolic blood pressure, diastolic blood pressure, uric acid, BMI, TG, TC is an important factor affecting baPWV, namely age, blood pressure high, Uric  acid is higher, the higher the TG value, the higher the baPWV value。 Conclusion the Logistic regression analysis indicated that the influencing factors of all variables are not ABI value, ABI value has no effect on serum lipid。 Multivariate linear regression analysis showed that age, systolic blood pressure, diastolic blood pressure, uric acid, BMI, TG, TC is an important factor affecting baPWV, the older, the higher the blood pressure,

uric acid is higher, the higher the TG value, baPWV value is high。 There is no correlation between the blood lipid and ABI conclusion age, systolic blood pressure, diastolic blood pressure, uric acid, BMI, TG, TC and baPWV, blood lipid and atherosclerosis have no obvious correlation。