摘要纳米金刚石硬度高、有良好耐磨性而且化学性质稳定，可作为填料提高材料的机械性 能，但其团聚问题极大限制了其应用发展。

本研究针对纳米金刚石易团聚问题，利用不同比例 PVP 与 HEMA 的共聚物对纳米金 刚石表面进行季铵化改性。通过 FTIR、1HNMR 对改性纳米金刚石结构和成分进行表征， 通过动态光散射和 TEM 对其粒径进行观测；此外，通过最小抑菌浓度对改性纳米金刚石的 抗菌性能进行表征。结果表明：季铵盐共聚物 PVP-HEMA 修饰到纳米金刚石表面，将纳 米金刚石团聚体分散的同时，并且赋予其优异的抗菌性能；其中，PVP-HEMA（9:1）季铵化 共聚物改性的纳米金刚石粒径最小，解团聚效果最好，抗菌效果也最优异(对大肠杆菌和 金黄色葡萄球菌 MIC 都为 62。5 μg/mL)。最后将 PVP-HEMA（9:1）季铵化共聚物改性的纳米 金刚石加入牙科修复树脂材料中，并测定其机械性能和抗菌性能。实验结果得出：纳米金 刚石添加量 0。3%时，树脂材料机械性能最佳；而抗菌性能随着添加量的增加而增加。76005

毕业论文关键词 纳米金刚石 解团聚 分散 牙科修复树脂

毕 业 设 计 说 明 书 外 文 摘 要

Title The application of nanodiamond on dental restoration resin

Abstract Nanodiamond with high hardness, good wear resistance and chemical stability can be used as filler to improve the mechanical performance of materials。 But the agglomeration problem greatly limits its application。

This study is based on nanodiamond reunion problems。 The nanodiamond surface functionlization were carried out by the quaternary ammonium copolymer PVP-HEMA in different proportion。 The structure and composition of functionalized nanodiamond were characterized by FTIR and 1HNMR。 The particle size was investigated through TEM and dynamic light scattering。 In addition, through the minimum inhibitory concentration, the antibacterial properties of the modified nanodiamond were characterized。 The results showed that the copolymer of PVP-HEMA were grafted onto nanodiamond surface successfully。 The

modification process not only settled the problems of agglomeration and poor  dispersion stability of ND but also rendered the nano-material antibacterial property。 Nanodiamond functionalized with PVP-HEMA (9:1) showed the best antibacterial property with MIC of 62。5 μg/mL against S。 aureus and E。 coli。 Nanodiamond functionalized with PVP-HEMA (9:1) was mixed with restoration resin material 。And the mechanical properties of dental restoration resin material were measured。 From its results, resin material mixed with nanodiamond had good mechanical   properties,   and   the   0。3%   was   the   best。   Through   the   minimum  inhibitory

concentration  ，antibacterial property of resin material increased as additive amount increased。

Keywords  Nanodiamond    Disaggregation    Dispersion    Dental restorative resin

第 I  页

目 录

1 综述 1

1。1 纳米金刚石的简介及其发展现状 1

1。2 牙科树脂复合材料介绍 3

1。3 季铵化纳米金刚石