In this paper, a new TMB synthesis route was developed by changing the reaction conditions and bromination and methylation reagents: the new vanillin process (Patent No 。: CN201610519452)。 This new vanillin method includes bromination, methoxylation, methylation (etherification) three-step reaction, that is vanillin as raw material, brominated brominated monochloride to get 5-bromo vanillin, and then chlorine And the methylation reaction with methyl chloride as the methylation reagent to obtain the final product 3,4,5-trimethoxy Benzaldehyde。

The chemical design for the new vanillin method The third step methylation (etherification) reaction with an annual output of 1,000 tons of 3,4,5-trimethoxybenzaldehyde workshop process design, will be based on small experimental data, and reference The relevant domestic industry engineering examples and industry standards, the results of the small test project to simulate amplification。

The design process includes the reaction section, the filter section, the methanol recovery section, the toluene extraction section, the alkali washing section, the toluene recovery section 

and the drying section。 The design of all the sections of the material balance, the reaction section, the methanol recovery section and the toluene recovery section of the heat balance。 The main equipment used in the chemical process is selected, the toluene distillation tower was designed, including the calculation of the number of theoretical plates, packing tower height calculation, tower diameter calculation。 According to the calculation results, the process pipelines and instrument flow chart, workshop layout plan, workshop elevation plan and toluene distillation tower equipment map are drawn。

This design is based on industry standards such as the technical design of process system engineering (HG / T 20570-1995) and the design of chemical plant equipment (HG 20546-1992), refer to "Chemical Process Design Handbook" and "Chemical Engineer Technology Book" The design requirements of the reference book。 This design can ensure the target yield and purity of 3,4,5-trimethoxybenzaldehyde, and strive to be related to the production and construction of the industry has a certain reference value。

Key words:3,4,5-trimethoxybenzaldehyde (TMB);Vanillin method; workshop process design

目 录 1

1 概述 1

1。1 设计项目名称 1

1。2 课题研究背景 1

1。3产品介绍及用途 1

1。4 产品、原料及中间体的主要物化性质及规格 3

1。4。1 丁香醛的物性数据 3

1。4。2 氯甲烷的物性数据 4

1。4。3 甲醇的物性数据 5

1。4。4 无水碳酸钠的物性数据 6

1。4。5 甲苯的物性数据 7

1。4。6 水的物性数据 8

1。4。7 氢氧化钠的物性数据 8

1。5 设计依据 9

2 工艺流程设计 10

2。1 生产工艺的论证和选择 10

2。1。1传统工艺路线介绍 10

2。1。1新型工艺路线介绍 10

2。2 过程条件简述 11

2。3工艺管道及仪表流程图 12

2。4 工艺操作说明