摘  要：阴离子在生态环境的保护,化学反应以及生物的各种进程上面有非常重要的作用，所以说阴离子的检测和识别是非常重要的。氟离子的应用范围非常广泛，对人体来说氟离子治疗骨质疏松以及预防龋齿，但是过量的摄入氟离子导致各种疾病，大量的摄入氟化物还会导致死亡，对于环境也是一样的。所以说对氟离子的检测也是非常重要的。82257

检测氟离子有色谱法、氟离子选择电极法、氟试剂比色法和氟离子荧光探针法等，而氟离子荧光探针法也是当前主流的研究方向，氟离子荧光探针主要分为氢键型；路易斯酸受体型；氢键和路易斯酸混合型。

本论文主要设计合成一种新型的氟离子荧光探针，通过合成荧光素原料9-氨基甲基蒽，以介孔氧化硅纳米粒子SBA-15为载体，并将其负载在氨基修饰的介孔氧化硅纳米粒子SBA-15上，再利用UV、FT-IR等一系列方法对荧光素与修饰后的纳米粒子进行表征。并且我们还进行了不同比例的SBA-15与9-氨基甲基蒽的配比，以此测试产物接枝率，从而找到最佳的反应配比。

毕业论文关键词：氟离子；荧光探针；SBA-15

Fabrication and Characterization of Fluoride - free Fluorescence Probe Based on SBA - 15

Abstract：Anions played a significant important role in the ecological environment protection, chemical reactions, biological processes and so on。 The technology of  anion detection and identification was meaningful and of great importance that had been widely employed in varieties of fields。Fluoride ion was applied not only in the fluoride treatment of osteoporosis in human bodies, but also in the prevention of dental caries, while an excessive intake of fluoride ion would cause diseases or even death, this is the same for the environment。 So that is also  important for anion detection。

The methods of detecting fluoride ion are selective electrode method, fluorine reagent colorimetric method and fluoride ion fluorescence probe method, and the fluoride ion fluorescence probe method is the mainstream research direction, fluoride ion fluorescent probe is pided intohydrogen bond;Lewis acid; hybrid Lewis acid/hydrogen-bond。

In this paper, a new type of fluoride ion fluorescent probe was designed and synthesized。 The mesoporous silica nanoparticles SBA-15 was used as a carrier and synthesized on the amino-modified mesoporous Silica nanoparticles on SBA-15, and then fluorescein and modified nanoparticles were characterized by UV and FT-IR。 And we also carried out a different ratio of SBA-15 and 9-aminomethyl anthracene in the ratio, in order to test the product grafting rate, so as to find the best reaction ratio。

Key Words: Fluoride ion,；Fluorescent probe；SBA-15

目录

1 绪论 1

1。1 引言 1

1。2 地方性氟中毒 1

1。2。1 燃煤染型氟中毒 1

1。2。2 饮水型氟中毒 2

1。2。3 饮茶型氟中毒 2

1。3 氟离子检测方法 2

1。3。1 色谱法 2

1。3。2 氟离子选择电极法 2

1。3。3 氟试剂比色法 3

1。3。4 氟离子荧光探针法 3

1。4 荧光探针 3

1。5 氟离子荧光探针 4

1。5。1 氢键型 4