氮杂金刚烷类化合物在含能材料、医药、催化领域都有广泛应用。本文详细介绍了 金刚烷及其衍生物的应用，简述了氮杂环化合物和氮杂金刚烷的合成现状，研究了 2,4,9- 三硝基-2,4,9-三氮杂-7-金刚烷醇硝酸酯的合成。77971

设计了以烯丙基溴化镁和氯甲酸乙酯为原料先合成三烯丙基甲醇，经臭氧化、还原 和缩合三步“一锅法”工艺，成功构建 2,4,9-三氮杂金刚烷骨架，再由催化脱苄乙酰化 和硝化反应成功合成了一种新型含能化合物 2,4,9-三硝基-2,4,9-三氮杂-7-金刚烷醇硝 酸酯，反应总收率 2。4%，为含能材料领域提供了一种具有应用前景的高能材料，并为氮 杂碳环笼状高能化合物的合成提供理论参考。

毕业论文关键词 含能化合物 氮杂金刚烷，笼状化合物，硝酸酯

毕 业 设 计 说 明 书 外 文 摘 要

Title Synthesis of Triazaadamantanes

Abstract Adamantane compounds unique cage-like structure caused concern in various fields and widely used in synthesis of functional materials medicines, catalysts and many other aspects。 The application of adamantanes and the synthesis of azaadamantane were introduced in detail。 Studied on the Synthesis of

2,4,9-trinitro-2,4,9-triazaadamantane-7-nitrate。

Designed with an allyl bromide and ethyl chloroformate as a raw material to synthesize triallylmethanol。 Then one-pot process of ozonization, reduction and condensation from triallylmethanol was successively constructed

2,4,9-triazaadamantane skeleton which was converted to a new energetic compound 2,4,9-trinitro-2,4,9-triazaadamantane-7-nitrate via debenzylization, acetylation and nitration with a total yield of 3。4%。The research of three

azaadamantane synthesis design and implementation of new routes, in order to provide a field of materials containing energetic material having a prospect, and to provide a theoretical reference for the synthesis of aza carbocyclic cage energetic compounds。

Keywords Energetic compound, Azaadamantane, Cage compound, Nitrate

目 次

1 绪论 1

1。1 引言 1

1。2 金刚烷类化合物及金刚烷类含能材料研究发展 1

1。2。1 研究意义及背景 1

1。2。2 金刚烷及衍生物的合成研究进展 2

1。2。3 多硝基金刚烷合成研究进展 5

1。3 氮杂环化类合物的研究现状 8

1。3。1 研究意义及背景 8

1。3。2 硝基氮杂环化合物的合成研究 9

1。4 氮杂金刚烷研究现状 10

1。4。1 研究意义及背景 11

1。4。2 一氮杂金刚烷的合成 11

1。4。3 二氮杂金刚烷的合成 12